Psychological and Brain Sciences Brown Bag Seminar: Kim Whitehead, University College London
Spontaneous Neural Activity in Human Neonates and Normal and Aberrant Brain Development
Kim Whitehead, University College London
Abstract: Neonatal animal models indicate that brain maturation is strongly dependent on coordinated spontaneous neural activity, which is sensitive to the sensory environment and sleep-wake state. Comparable patterns of neural activity are observed in human neonates, using electroencephalography (EEG) recordings. In the first part of my talk I will outline how spontaneous neural activity may promote normative sensory development across the equivalent of late human gestation. In the second part of my talk I will discuss how pre-term birth may modify spontaneous neural activity, via altered sensory experience, sleep-wake cycling, and acquired ischemic brain injury, and how this could partly underlie subsequent adverse neurological outcome.